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1,1-Dibromo-1-alkenes as Valuable Partners in the Copper-Catalyzed Direct Alkynylation of Azoles

  作者 BERCIANO BEATRIZ PACHECO; LEBREQUIER SABRINA; BESSELIEVRE FRANCOIS; PIGUEL SANDRINE  
  选自 期刊  Organic Letters;  卷期  2010年12-18;  页码  4038-4041  
  关联知识点  
 

[摘要]The copper-catalyzed direct alkynylation of azoles with 1,1-dibromo-1-alkenes as electrophiles is described. These easily accessible substrates are a useful addition to the field of direct alkynylations in an efficient and functional group tolerant reaction to provide a straightforward entry to diverse alkynyl heterocycles.

 
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