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Four Nucleophilic Additions to Alkenynedioic Acid Derivatives in Tandem; Efficient One-Pot Synthesis of Bicyclo[4.2.0]octenols

  作者 HATA TAKESHI; IMADE HADUKI; URABE HIROKAZU  
  选自 期刊  Organic Letters;  卷期  2012年14-10;  页码  2450-2453  
  关联知识点  
 

[摘要]When alkenynedioic acid derivatives were treated with a Grignard reagent, tandem cyclization and the incorporation of two molecules of the Grignard reagent occurred to give stereodefined bicyclo[4.2.0]octenols via four nucleophilic additions.

 
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