Three-component, one-pot sequential synthesis of 1,3-disubstituted 5-arylhydantoins.

[摘要]：Reaction of carbodiimides with a-bromo(chloro)arylacetates produces N,N'-substituted 5-arylhydantoins under very mild conditions and with high yields. When the carbodiimides are generated in situ by Staudinger reaction, the process becomes a 1-pot, 3-component sequential synthesis of libraries of differently substituted 5-arylhydantoins.

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