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NHC-Mediated Chlorination of Unsymmetrical Ketenes: Catalysis and Asymmetry

  作者 DOUGLAS JAMES; LING KENNETH B; CONCELLON CARMEN; CHURCHILL GWYDION; SLAWIN ALEXANDRA M Z; SMITH ANDREW D  
  选自 期刊  European Journal of Organic Chemistry;  卷期  2010年-30;  页码  5863-5869  
  关联知识点  
 

[摘要]NHCs promote the efficient chlorination of unsymmetrical disubstituted ketenes with a range of chlorinating agents; chiral NHCs display promising levels of asymmetric induction in the chlorination process with up to 61 % ee observed using 2,3,4,5,6,6-hexachlorocyclohexa-2,4-dienone.

 
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