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Protein Tethering into Multiscale Geometries by Covalent Subtractive Printing

  作者 Coyer, SR Coyer, SR; Delamarche, E; Garcia, AJ  
  选自 期刊  ADVANCED MATERIALS;  卷期  2011年23-13;  页码  1550-1553  
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[摘要]High-resolution patterns of proteins at multiple length scales are printed by a facile and flexible strategy using a flat elastomeric stamp and direct covalent immobilization onto mixed self-assembled monolayers of tri(ethylene glycol)- and carboxylic acid-hexa(ethylene glycol)terminated alkanethiols on gold-coated substrates. This is a robust method for generating complex protein arrays with precise control over micrometer- and nanometer-scale pattern geometries while maintaining a protein-adsorption-resistant background.

 
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