A Rapid and Convenient Microwave-Promoted Synthesis of 3,5-Disubstituted 2-Chloropyridines and Their Conversion into Tetrazolo[1,5-a]pyridines

[摘要]：This work describes a rapid and convenient synthesis of 3,5-disubstituted 2-chloropyridines from various alpha,beta-unsaturated ketoximes utilizing the Vilsmeier reaction under microwave irradiation. The 3,5-disubstituted 2-chloropyridines were further converted into tetrazolo[1,5-alpha]pyridines by a microwave-mediated solid-phase reaction. The products were isolated in good yields within a very short reaction time.

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