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Rewiring of Genetic Networks in Response to DNA Damage

  作者 Bandyopadhyay, S; Mehta, M; Kuo, D; Sung, MK; Chuang, R; Jaehnig, EJ; Bodenmiller, B; Licon, K; Copeland, W; Shales, M; Fiedler, D; Dutkowski, J; Guenole, A; van Attikum, H; Shokat, KM; Kolodner, RD; Huh, WK; Aebersold, R; Keogh, MC; Krogan, NJ; Ideker, T  
  选自 期刊  Science;  卷期  2010年330-6009;  页码  1385-1389  
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[摘要]Although cellular behaviors are dynamic, the networks that govern these behaviors have been mapped primarily as static snapshots. Using an approach called differential epistasis mapping, we have discovered widespread changes in genetic interaction among y

 
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