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A New Method for the Benzylic Oxidation of Alkylarenes Catalyzed by Hypervalent Iodine(III)

  作者 XU YUAN; YANG ZHENPING; HU JIANTAO; YAN JIE  
  选自 期刊  Synthesis;  卷期  2013年45-3;  页码  370-374  
  关联知识点  
 

[摘要]A convenient and simple procedure is described for the oxidation of the benzylic C-H moiety of alkylarenes to give the corresponding aryl ketones, using tert-butyl hydroperoxide and m-chloroperoxybenzoic acid in the presence of a catalytic amount of the hypervalent iodine reagent, (diacetoxyiodo)benzene. The reactions typically occur in good yields in 2,2,2-trifluoroethanol as the solvent and at room temperature.

 
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