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Synthesis of Oxazoles from Enamides via Phenyliodine Diacetate-Mediated Intramolecular Oxidative Cyclization

  作者 ZHENG YUNHUI; LI XUMING; REN CHENGFENG; ZHANGNEGRERIE DAISY; DU YUNFEI; ZHAO KANG  
  选自 期刊  Journal of Organic Chemistry;  卷期  2012年77-22;  页码  10353-10361  
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[摘要]A group of functionalized oxazoles were synthesized in moderate to good yields from enamides via phenyliodine diacetate (PIDA)-mediated intramolecular cyclization. The main advantageous features of the present method include its broad substrate scope and the heavy-metal-free characteristic of the oxidative carbon-oxygen bond formation process.

 
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