[摘要]：Palladium-catalyzed Suzuki-Miyaura coupling reactions of ethyl alpha-bromo-alpha-fluoroacetate with various structurally diverse arylboronic acids using a phosphine ligand proceeded smoothly to afford alpha-aryl-alpha-fluoroacetates in moderate to good yields. This method provides a practical and efficient route to diverse alpha-mono-fluorinated alpha-arylcarbonyl compounds. |
