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Trigoxyphins H and I: Two new daphnane diterpenoids from Trigonostemon xyphophylloides

  作者 Yang, B; Chen, GY; Song, XP; Yang, LQ; Han, CR; Wu, XY; Li, XM; Zou, BY  
  选自 期刊  Bioorganic & Medicinal Chemistry Letters;  卷期  2012年22-11;  页码  3828-3830  
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[摘要]Two new daphnane diterpenoids (1 and 2), together with four known analogues (3-6) were isolated from Trigonostemon xyphophylloides. Their structures were elucidated by spectroscopic analysis. Compounds 1 and 2 were evaluated for in vitro cytotoxic activities against the SPCA-1 (human lung cancer) and BEL-7402 (human hepatocellular carcinoma) cancer cell lines. Trigoxyphin I (2) showed modest cytotoxicity against two tumor cell lines. (C) 2012 Published by Elsevier Ltd.

 
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