| |
[摘要]：A review. The discovery of new biol. active mols. contributes to the development of basic scientific concepts in the field of biol. sciences. These compds. often lead to the development of valuable drugs, and to new pharmacol. reagents. They also lead to a better understanding of ecol. phenomena. Newly discovered substances can even be responsible for the creation of new scientific fields. Due to the radically different habitats of marine organisms, several notable examples of secondary metabolites from marine organisms have been isolated. Two of the most remarkable properties of these compds. are their structural and physiol. diversities. Palytoxin is a polyol compd. that shows extreme acute toxicity. Halichondrins are remarkable antitumor macrolides from sponge. Pinnatoxins, potent shellfish poisons, cause food poisoning. The compds. controlling the ecol. behaviors of coral reveal to us a wonder of nature. And, the compds. produced by symbiotic microorganisms always inspire us by chem. interests. This paper describes bioorg. studies that are helping to develop new research fields. |
|
