ASYMMETRIC SYNTHESIS OF 2-PROPYLISOFAGOMINE USING ALLYLIC HYDROXY GROUP ACCELERATED RING-CLOSING ENYNE METATHESIS

[摘要]：An asymmetric synthesis of 2-propylisofagomine 5 using allylic hydroxy group accelerated ring-closing enyne metathesis (AHA-RCEM) was conducted with high diastereoselectivity in 13% overall yield starting from the commercially available (E)-hex-2-ol.

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