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A Novel Multicomponent Tandem Phosphine-Catalyzed Umpolung Reaction: Facile Access to Highly Functionalized alpha-Aminonitriles

  作者 CHEN JIANMING; FANG YIN ZHI; WEI ZHONGLIN; LIAO WEIWEI  
  选自 期刊  Synthesis;  卷期  2012年44-12;  页码  1849-1853  
  关联知识点  
 

[摘要]The first phosphine-catalyzed multicomponent tandem Strecker-gamma-umpolung-addition reaction has been developed, which provides a facile access to functionalized allylic alpha-aminonitriles. The reaction is highly efficient, rapid, versatile and economical, and it is hoped that it will find great practical application in organic synthesis.

 
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