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An Efficient Synthesis of Pyrazolo[3,4-b]quinolin-5(6H)-one Derivatives in Ionic Liquid

  作者 SHI DAQING; YANG FANG  
  选自 期刊  Journal of Heterocyclic Chemistry;  卷期  2011年48-2;  页码  308-311  
  关联知识点  
 

[摘要]A series of 4-aryl-3,7,7-trimethyl-1-phenyl-7,8-dihydro-1H-pyrazolo[3,4-b]quinolin-5 (6H)-ones were synthesized via the three-component reaction of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexandione and 5-amino-3-methyl-1-phenylpyrazole in ionic liquid without using any catalyst. This protocol has the advantages of easier work-up, milder reaction conditions, short reaction time, and environmentally benign procedure.

 
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