Diversity Oriented Approach to Polycyclic Compounds through the Diels-Alder Reaction and the Suzuki Coupling

[摘要]：A diversity oriented strategy has been demonstrated to deliver small drug like molecules using alkylation, DielsAlder reaction, and SuzukiMiyaura cross-coupling as key steps. This methodology allows access a wide range of molecules using simple scaffolds such as indanes, tetralins and tetrahydroisoquinolines, which can enhance the chemical space for potential therapeutic molecules.

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