Palladium-Catalyzed Direct 1,4-Addition of Heteroarenes to alpha,beta-Unsaturated Ketones via C-H Activation

[摘要]：Palladium-catalyzed direct conjugate additions of heteroarenes to alpha,beta-unsaturated ketones via C-H activation are described. The reactions of heteroarenes with alpha,beta-unsaturated ketones proceeded smoothly in the presence of PdCl2 as a catalyst under mild conditions to give the corresponding Michael adducts in moderate to excellent yields.

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