Convenient Synthesis of Substituted 2-(2-Iminocoumarin-3-yl)thieno[2,3-d]pyrimidin-4-ones

[摘要]：The interaction of both 2-iminocoumarin-3-carbonitriles and 2-iminocoumarin-3-carbothioamides with 2-aminothiophen-3-carboxamides lead to formation of 3-(4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)2-iminocoumarins in two steps. The simplicity of the procedure, as well as the high yields of the target products make this method to be a good alternative of Knoevenagel condensation for the synthesis of 3-(4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-2-yl)-2-iminocoumarins.

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