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Precise and programmable manipulation of microbubbles by two-dimensional standing surface acoustic waves

  作者 Meng, L; Cai, FY; Chen, JJ; Niu, LL; Li, YM; Wu, JR; Zheng, HR  
  选自 期刊  Applied Physics Letters;  卷期  2012年100-17;  页码  173701-173701  
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[摘要]A microfluidic device is developed to transport microbubbles (MBs) along a desired trajectory in fluid by introducing the phase-shift to a planar standing surface acoustic wave (SSAW). The radiation force of SSAW due to the acoustic pressure gradient modulated by a phase-shift can move MBs to anticipated potential wells in a programmable manner. The resolution of the transportation is approximately 2.2 mu m and the estimated radiation force on the MBs is on the order of 10(-9) N. This device can be used for manipulation of bioparticles, cell sorting, tissue engineering, and other biomedical applications. (C) 2012 American Institute of Physics. [http://dx.doi.org/10.1063/1.4704922]

 
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