Cleistanone: A Triterpenoid from Cleistanthus indochinensis with a New Carbon Skeleton

[摘要]：Cleistanone (1) was isolated from the leaves of Cleistanthus indochinensis and features a new type of triterpenoid carbon skeleton. Its structure was confirmed by X-ray diffraction analysis. A plausible biosynthetic pathway was proposed for 1 and is thought to proceed through a Wagner-Meerwein rearrangement. Cleistanone (1) was found to show cytotoxic activity against human oral epidermoid carcinoma KB cells.

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