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Exploring the Unique Reactivity of Diazoesters: An Efficient Approach to Chiral beta-Amino Acids

  作者 TROST BARRY M; MALHOTRA SUSHANT; ELLERBROCK PASCAL  
  选自 期刊  Organic Letters;  卷期  2013年15-3;  页码  440-443  
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[摘要]The development of a highly stereospecific process for the C-O to C-N exchange with retention of configuration is described. This transformation enables access to optically enriched beta-amido-alpha-diazoesters. These products are transformed to beta-amino acids not readily accessible using known methods.

 
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