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Safe and Efficient Ritter Reactions in Flow

  作者 BRANDT JOHAN C; ELMORE SIMON C; ROBINSON RICHARD I; WIRTH THOMAS  
  选自 期刊  SYNLETT;  卷期  2010年-20;  页码  3099-3103  
  关联知识点  
 

[摘要]Efficient mixing, temperature control and small environmental exposures allow reactions carried out in microfluidic devices to perform superior to their batch-type counterparts in conventional flasks. The Ritter reaction has been optimised for flow conditions leading to short reaction times and higher yields and also is more feasible with regards to safety, productivity and tolerance towards substrate functionalities.

 
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