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RAPID TRIFLUOROMETHYLATION OF INDOLE DERIVATIVES

  作者 MIYAZAKI AYAKO; SHIMIZU RYO; EGAMI HIROMICHI; SODEOKA MIKIKO  
  选自 期刊  Heterocycles;  卷期  2012年86-2;  页码  979-983  
  关联知识点  
 

[摘要]Rapid trifluoromethylation of indole derivatives was achieved using trimethylsilyltriflate as the catalyst. Good to high yields were observed within only 5 min at room temperature. This reaction system is able to provide not only the mono-trifluoromethylated products, but also the di-trifluoromethylated derivatives, because of its high reaction efficiency.

 
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