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Synthesis and characterization of new C-alpha,C-alpha-disubstituted (diarylaminomethyl)phosphonates

  作者 Cristau, HJ; Lambert, JM; Pirat, JL  
  选自 期刊  Synthesis;  卷期  1998年-8;  页码  1167-1170  
  关联知识点  
 

[摘要]A convenient and efficient three-step procedure for the preparation of N-protected or unprotected C-alpha,C-alpha-disubstituted (diarylaminomethyl)phosphonates 1 is reported. This method allows diversification of the substituents on the carbon in the alpha-position to the phosphorus, as well as the protective group on the amine and the phosphonate ester group.

 
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