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Enantioselective synthesis of 3,3-disubstituted indolines via asymmetric intramolecular carbolithiation in the presence of (-)-sparteine.

  作者 Groth, Ulrich;Koettgen, Peter;Langenbach, Philipp;Lindenmaier, Andreas;Schuetz, Thorben;Wiegand, Matthias;  
  选自 期刊  SYNLETT;  卷期  2008年-9;  页码  1301-1304  
  关联知识点  
 

[摘要]N-Allyl-N-benzyl-2-bromoanilines underwent an asym. intramol. carbolithiation in the presence of tert-BuLi and (-)-sparteine yielding 3,3-disubstituted indolines.

 
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