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Light-Induced Isomerization of Apoptolidin A leads to Inversion of C2-C3 Double Bond Geometry

  作者 BACHMANN BRIAN O; MCNEES RUTH; MELANCON BRUCE J; GHIDU VICTOR P; CLARK RACHEL; CREWS BRENDA C; DEGUIRE SEAN M; MARNETT LAWRENCE J; SULIKOWSKI GARY A  
  选自 期刊  Organic Letters;  卷期  2010年12-13;  页码  2944-2947  
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[摘要]The isolation, characterization, and cytotoxicity against H292 cells of apoptolidin G are reported. Apoptolidin G is shown to be derived by a light-induced isomerization of the C2-C3 carbon-carbon double bond of apoptolidin A.

 
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