【文章名】Synthesis of 3-fluoro-2,5-disubstituted furans and further derivative reactions to access fluorine-containing 3,3'-bifurans and tetrasubstituted furans.
Synthesis of 3-fluoro-2,5-disubstituted furans and further derivative reactions to access fluorine-containing 3,3'-bifurans and tetrasubstituted furans.
[摘要]：2,5-Disubstituted 3-fluorofurans were synthesized in 42-99% yield via DBU-promoted cyclization of electron-deficient gem-difluorohomopropargyl alcs. Starting from these compds., a series of fluorinated 3,3'-bifurans and tetrasubstituted furans were also prepd. through a fluorine-directed ortho-functionalization process.
