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How Telomeres Solve the End-Protection Problem

  作者 de Lange, T  
  选自 期刊  Science;  卷期  2009年326-5955;  页码  948-952  
  关联知识点  
 

[摘要]The ends of eukaryotic chromosomes have the potential to be mistaken for damaged or broken DNA and must therefore be protected from cellular DNA damage response pathways. Otherwise, cells might permanently arrest in the cell cycle, and attempts to "repair

 
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