[摘要]：Enantioselective hydrogenation of quinoline derivs. catalyzed by phosphine-free chiral cationic Cp*Ir(OTf)(CF3TsDPEN) complex (CF3TsDPEN = N-(p-trifluoromethylbenzenesulfonyl)-1,2-diphenylethylene-diamine) afforded the 1,2,3,4-tetrahydroquinoline derivs., e.g., I, in up to 99% ee. The reaction could be carried out with a substrate-to-catalyst molar ratio as high as 1000 in undegassed methanol and with no need for inert gas protection.
