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Concise Synthesis of the Oxapentacyclic Core of Cortistatin A

  作者 YU FANGMIAO; LI GUOZHI; GAO PENG; GONG HONGJU; LIU YINGHUA; WU YONGMING; CHENG BIN; ZHAI HONGBIN  
  选自 期刊  Organic Letters;  卷期  2010年12-22;  页码  5135-5137  
  关联知识点  
 

[摘要]A concise synthetic approach for constructing the oxapentacyclic framework of cortistatin A is described. The synthesis features a furan-oxyallyl [4 + 3] cycloaddition and double-intramolecular aldol reactions. In addition, an interesting core structure was obtained in 11 steps from furan by using our method.

 
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