Highly cis-Diastereoselective Synthesis of Coumarin-Based 2,3-Disubstituted Dihydrobenzothiazines by Organocatalysis

[摘要]：An efficient and organocatalyzed asymmetric reaction of phenacyl halides with coumarin-based dihydrobenzothiazoles was developed to afford cis-2,3-disubstituted 3,4-dihydro-2H-benzothiazines. This method provides a one-step and highly diastereoselective route to a wide variety of coumarin-based 3,4-dihydro-2H-benzothiazines using the cheap and commercially available Cinchona alkaloid quinine hydrochloride.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内