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[摘要]：Four caffeoylquinic acid (CQA) derivatives, 5-O-caffeoylquinic acid (1), 3,5-di-O-caffeoylquinic acid (3), 4,5-di-O-caffeoylquinic acid (4), and 3,4,5-tri-O-caffeoylquinic acid (5), have been isolated from Artemisia herba-alba growing wild in Algeria, using the on-line HPLC?DAD?DPPH radical-scavenging detection technique as guidance. In the course of the purification work, the non-frequent (E)-2-(beta-D-glucopyranosyloxy)-4-methoxycinnamic acid (2) has also been isolated. The CQAs showed fair-to-good antioxidant activities determined by the DPPH. scavenging assay. The structures of the five isolated compounds were determined by spectroscopic methods. The on-line HPLC?DAD?DPPH technique allowed for a rapid pinpointing of antioxidants in the studied plant, accomplishing the facile guided isolation of the target molecules. Algerian A. herba-alba could be an interesting source of natural antioxidants that deserve further work. |
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