Synthesis and Antimicrobial Activity of New Thiazole Derivatives and Their Glucoside and Acyclic Nucleoside Analogs

[摘要]：New thiazole derivatives were synthesized. The N-substituted acyclic nucleoside analogs and the substituted glucosides were also prepared. The synthesized compounds were tested for their antimicrobial activity against Candida albicans, Escherichia coli, Staphylococcus aureus, and Bacillus subtilis. The obtained results indicated that most of the tested compounds exhibited low to high moderate activities whereas few compounds were found to exhibit little or no activity against the tested microorganisms.

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