A CONVENIENT SYNTHESIS OF NOVEL SPIROISOINDOLONE gamma-HALOBUTYROLACTONES VIA HALOCYCLIZATION OF gamma-ETHYLENIC ACIDS

[摘要]：gamma-Ethylenic carboxylic acids are cyclized to spirolsoindolone gamma-halomethylbutyrolactones, in the presence of NBS or NIS and K2CO3. The corresponding haloaspirobutyrolactones were isolated in high yields (57-95%).

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