DDQ/TBHP-Induced Oxidative Cyclization Process: A Metal-Free Approach for the Synthesis of 2-Phenylquinazolines

[摘要]：Various 2-phenylquinazoline derivatives were synthesized under metal-free conditions from readily available 2-aminophenyl ketones and benzylamines via condensation and oxidative cyclization using 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as a versatile reagent. The reaction gave the corresponding 2-phenylquinazoline derivatives in good to excellent yields (up to 92%).

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