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RUTHENIUM TETROXIDE OXIDATION OF N,N '-DIBOC HEXAHYDROPYRIDAZINES

  作者 KANAME MAMORU; YOSHIFUJI SHIGEYUKI; SASHIDA HARUKI  
  选自 期刊  Heterocycles;  卷期  2009年79-1;  页码  647-658  
  关联知识点  
 

[摘要]The ruthenium tetroxide (RuO4) oxidation of the 3-substituted N,N'-diBochexahydropyridazines gave the 6-oxohexahydropyridazines in good to high yields, whereas the oxidation of the unsubstituted ones also gave the 3,6-dioxo derivatives. The 3,6-cis-disubstituted pyridazines were essentially oxidized to give the 3-hydroxypyridazines; no oxidation of the trans-derivative occurred.

 
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