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Total Synthesis of (+/-)-Kainic Acid: A Photochemical C-H Carbamoylation Approach

  作者 KAMON TAKUMA; IRIFUNE YAYOI; TANAKA TETSUAKI; YOSHIMITSU TAKEHIKO  
  选自 期刊  Organic Letters;  卷期  2011年13-10;  页码  2674-2677  
  关联知识点  
 

[摘要]A novel photochemical C-H carbamoylation of an octahydroisolndole derivative with PhNCO has allowed the authors to provide a unique access to a highly functionalized proline motif from which total synthesis of (+/-)-kainic acid, a bioactive marine alkaloid, has been accomplished.

 
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