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A convenient one-pot synthesis of 7-trifluoromethyl-substituted imidazo[4,5-b]pyridines.

  作者 Wesch, Thomas;Iaroshenko, Viktor O.;Groth, Ulrich;  
  选自 期刊  SYNLETT;  卷期  2008年-10;  页码  1459-1462  
  关联知识点  
 

[摘要]This communication describes a practical and facile one-pot approach for the synthesis of 7-trifluoromethyl-substituted imidazo[4,5-b]pyridines by the reaction of in situ generated 5-aminoimidazole and a 1,3-CCC bis-electrophile, diketone.

 
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