Influence of Quercetin-rich Onion Peel Extracts on Adipokine Expression in the Visceral Adipose Tissue of Rats

[摘要]：We examined the effects of quercetin-rich onion peel extract supplementation on adipokine expressions from adipose tissues in a diet-induced obese animal model. Male Sprague-Dawley rats (n?=?24) were randomly assigned into control (n?=?8), high fat diet (HF, n?=?8) and high fat diet with onion peel extract (HFOE, n?=?8). After 8?weeks, serum biochemical parameters, weights of adipose tissues (epididymal, perirenal and mesenteric fats) and adipokine mRNA levels (adiponectin, IL (interleukin)-6 and visfatin) along with PPAR (peroxisome proliferator-activated receptor) ?2 from adipose tissues were measured. After the 8?week supplementation, mesenteric fat weights were lower in the HFOE group than the HF group (p?

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