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Minimal and Null Predictive Effects for the Most Popular Blood Biomarkers of Cardiovascular Disease

  作者 Ioannidis, JPA; Tzoulaki, I  
  选自 期刊  Circulation Research;  卷期  2012年110-5;  页码  658-662  
  关联知识点  
 

[摘要]At least 10 cardiovascular biomarkers that can be measured in blood have accrued more than 6000 published related papers each. A systematic evaluation of the evidence suggests that they have limited or no predictive ability for cardiovascular disease and suggests the need for a paradigm shift in testing and qualifying biomarkers and in the expectations surrounding them.

 
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