个性化文献订阅>期刊> European Journal of Medicinal Chemistry
 

Synthesis and in vitro cytotoxic evaluation of some thiazolylbenzimidazole derivatives

  作者 Luo, Y; Xiao, F; Qian, SJ; Lu, W; Yang, B  
  选自 期刊  European Journal of Medicinal Chemistry;  卷期  2011年46-1;  页码  417-422  
  关联知识点  
 

[摘要]A novel kind of thiazolylbenzimidazole derivatives were designed and synthesized and evaluated for their antitumor activity against SMMC-7721 and A549 cell lines. Most compounds showed good antitumor activities, and compound lib displayed remarkable in vitro anticancer activity comparable to taxol. The preliminary structure-activity relationship of these benzimidazole derivatives was discussed based on the experimental data obtained. (C) 2010 Elsevier Masson SAS. All rights reserved.

 
      被申请数(0)  
 

[全文传递流程]

一般上传文献全文的时限在1个工作日内