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Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

  作者 Ginhoux, F; Greter, M; Leboeuf, M; Nandi, S; See, P; Gokhan, S; Mehler, MF; Conway, SJ; Ng, LG; Stanley, ER; Samokhvalov, IM; Merad, M  
  选自 期刊  Science;  卷期  2010年330-6005;  页码  841-845  
  关联知识点  
 

[摘要]Microglia are the resident macrophages of the central nervous system and are associated with the pathogenesis of many neurodegenerative and brain inflammatory diseases; however, the origin of adult microglia remains controversial. We show that postnatal h

 
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