Synthesis of a xylo-puromycin analogue.

[摘要]：N6-Bis-demethylated xylo-puromycin analog I was synthesized through 6 steps in 56% yield from adenosine, involving a Mattocks bromoacetylation, a regio- and stereoselective ribo-epoxide ring opening with NaN3, and an efficient Staudinger-Vilarrasa reaction to couple the amino acid to an azide precursor.

[全文传递流程]：

一般上传文献全文的时限在1个工作日内