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An Analytical Solution to the Kinetics of Breakable Filament Assembly

  作者 Knowles, TPJ; Waudby, CA; Devlin, GL; Cohen, SIA; Aguzzi, A; Vendruscolo, M; Terentjev, EM; Welland, ME; Dobson, CM  
  选自 期刊  Science;  卷期  2009年326-5959;  页码  1533-1537  
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[摘要]We present an analytical treatment of a set of coupled kinetic equations that governs the self-assembly of filamentous molecular structures. Application to the case of protein aggregation demonstrates that the kinetics of amyloid growth can often be domin

 
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