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Regioselective Arylation and Alkynylation of 2,3-Dibromo-1H-inden-1-one by Suzuki-Miyaura and Sonogashira Cross-Coupling Reactions

  作者 Khera, RA; Hussain, M; Hung, NT; Eleya, N; Feist, H; Villinger, A; Langer, P  
  选自 期刊  Helvetica Chimica Acta;  卷期  2012年95-3;  页码  469-482  
  关联知识点  
 

[摘要]Suzuki?Miyaura reactions of 2,3-dibromo-1H-inden-1-one afforded a wide range of arylated 1H-inden-1-ones. Sonogashira cross-coupling reactions gave alkynylated indenones. The reactions proceeded with very good regioselectivity in the less sterically hindered and more electron-deficient position 3.

 
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