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Expeditious Synthesis of Phenanthridines from Benzylamines via Dual Palladium Catalysis

  作者 MAESTRI GIOVANNI; LARRAUFIE MARIEHELENE; DERAT ETIENNE; OLLIVIER CYRIL; FENSTERBANK LOUIS; LACOTE EMMANUEL; MALACRIA MAX  
  选自 期刊  Organic Letters;  卷期  2010年12-24;  页码  5692-5695  
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[摘要]A method for the synthesis of phenanthridines from benzylamines and aryl iodides which uses a dual palladium-catalyzed process is developed. The domino sequence ends via an intramolecular amination and an oxidative dehydrogenation. No protecting group or prefunctionalization of the amine is required, and the process uses dioxygen as the terminal oxidant.

 
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