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[摘要]:An efficient and mild method is developed for the deprotection of bulky (trialkylsilyl)acetylenes. Treatment of 1-(triisopropylsilyl)acetylenes With Silver fluoride, followed by hydrolysis of the intermediate silver acetylide with organic or inorganic acids, produces terminal acetylenes in good to excellent yields. The reactions are chemoselective and Various functional groups are tolerated. |
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