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Efficient Fluoride-Mediated Synthesis of 5-Amino-Substituted Isothiazoles

  作者 ZUBENKO YURI S; POTKIN VLADIMIR I  
  选自 期刊  Synthesis;  卷期  2009年-14;  页码  2361-2364  
  关联知识点  
 

[摘要]Fluoride-mediated nucleophilic substitution reactions of teri-butyl 4,5-dichloroisothiazole-3-carboxylate with various amines occur under mild conditions yielding 5-(alkylamino)isothiazoles in moderate to high yields.

 
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