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A Novel Procedure for the Synthesis of Benzo[b][1,8]naphthyridine-3-carboxylate Derivatives from Morita-Baylis-Hillman Adduct Acetates

  作者 ZHONG WEIHUI; LIN FULIANG; CHEN RENER; SU WEIKE  
  选自 期刊  Synthesis;  卷期  2009年-14;  页码  2333-2340  
  关联知识点  
 

[摘要]A novel procedure has been designed for the preparation of benzo[b][1,8]naphthyridine-3-carboxylate derivatives from the reaction of Morita-Baylis-Hillman adduct acetates with primary amines, ammonium acetate or benzenesulfonamides. The approach, which involves readily available starting materials and mild reaction conditions, gives excellent yields after a convenient workup procedure.

 
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