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Highly Stereoselective Synthesis of 2,3-Unsaturated Thioglycopyranosides Employing Molecular Iodine

  作者 REDDY BASI V SUBBA; DIVYAVANI CH; YADAV JHILLU S  
  选自 期刊  Synthesis;  卷期  2010年-10;  页码  1617-1620  
  关联知识点  
 

[摘要]Molecular iodine has been utilized for the first time for the thioglycosidation of D-glycals with various thiols to afford the corresponding 2,3-unsaturated thioglycosides in high yields. In the case of tri-O-acetyl-D-glucal, the a-anomer was obtained exclusively. The use of readily available iodine makes this method quite simple, more convenient, and practical.

 
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